Condition guide

ALS (Amyotrophic lateral sclerosis) - Overview

Also known as ALS or Lou Gehrig's disease, a progressive motor neuron disease affecting voluntary muscle control.

Illustration of a patient speaking with a clinician by video

Symptoms

  • Muscle cramps or twitching
  • Weakness beginning in limbs
  • Difficulty speaking or swallowing
  • Respiratory decline
  • Muscle atrophy

Causes & Risk Factors

  • Genetic mutations (SOD1, C9orf72)
  • Age (40-60)
  • Male gender
  • Environmental toxins

Diagnosis

  • EMG and nerve conduction
  • MRI to exclude other causes
  • Neurological exam
  • Swallow and respiratory function tests

Effective Treatment Options

  • Riluzole or edaravone
  • Physiotherapy for mobility and safety
  • Speech and swallow therapy
  • Respiratory support
  • Palliative care

Frequently Asked Questions

Is ALS fatal?

Yes, most patients survive 2-5 years after diagnosis, though new treatments may extend life.

Can therapy help?

Yes, therapy helps maintain mobility, independence, and comfort.

Explore related physiotherapy services

Learn about assessment, rehabilitation and consultation preparation in these treatment guides.

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